
Knights named 2020 Highly Cited Researcher
Associate Professor Knights is one of the most influential researchers in his fields, according to analysis of citation counts by Clarivate Analytics.

When two are better than one: Why some gene duplicates are retained while others perish
New study from the Myers Lab finds that gene “backups” more likely when encoded proteins have little room for change.

When cancer cells can’t make their own fat, they eat more of it, Myers Lab study finds
A switch in fat metabolism from production to import could be exploited for cancer treatment, researchers say.

Immigration to the United States changes a person’s microbiome
The study of communities migrating from Southeast Asia to the United States could provide insight into some of the metabolic health issues affecting immigrants to the country.
Research in this area explores the use of computational methods to better categorize, visualize, and model biological data and systems. These problems often involve massive, high-dimensional datasets and their solutions draw from many disciplines of computer science including database management, data mining, machine learning, and algorithmic optimization. Research in this group includes algorithms for sequence and structure analysis, protein structure prediction, virtual screening and lead discovery, data modeling of scientific applications, DBMS (database management system) extensions in support of brain image and proteomics analyses, and building predictive models for effective disease diagnoses. The research group has increasing collaboration with the College of Biological Sciences, the Medical School, and the Mayo Clinic.
Faculty








Labs and selected projects
- Bioinformatics George Karypis
- Bioinformatics and Computational Biology Vipin Kumar
- Chemical Informatics George Karypis
- Computational Biology Rui Kuang
- Karypis Lab
- Knights Lab
- Principal Research Projects Daniel Boley
Latest research projects, publications, and talks

Conversational Agent for Daily Living Assessment Coaching [conference paper]
Posted January 7, 2021
Aditya Gaydhani (M.S. student), Raymond Finzel, Sheena Dufresne, Maria Gini (professor), Serguei Pakhomov
AI4Function Workshop, International Joint Conference on Artificial Intelligence (IJCAI)

A National Research Agenda for Intelligent Infrastructure: 2021 Update [preprint]
Posted January 1, 2021
Daniel Lopresti, Shashi Shekhar (professor)

More Trees or Larger Trees: Parallelizing Monte Carlo Tree Search [journal]
Posted December 30, 2020
Erik S Steinmetz (Ph.D. 2016), Maria Gini (professor)
IEEE Transactions on Games

The structure of behavioral data [preprint]
Posted December 23, 2020
Aurélien Defossez, Morteza Ansarinia, Brice Clocher, Emmanuel Schmück, Paul Schrater (associate professor), Pedro Cardoso-Leite

Robotics Enabling the Workforce [preprint]
Posted December 16, 2020
Henrik Christensen, Maria Gini (professor), Odest Chadwicke Jenkins, Holly Yanco

Distant-Supervised Slot-Filling for E-Commerce Queries [preprint]
Posted December 15, 2020
Saurav Manchanda (Ph.D. 2020), Mohit Sharma (Ph.D. 2017), George Karypis (professor)

Comparing Generic and Community-Situated Crowdsourcing for Data Validation in the Context of Recovery from Substance Use Disorders [preprint]
Posted December 13, 2020
Sabirat Rubya (Ph.D. student), Joseph Numainville (undergraduate research assistant), Svetlana Yarosh (associate professor)

RegulaTOR: A Powerful Website Fingerprinting Defense [preprint]
Posted December 11, 2020
James K Holland (Ph.D. student), Nicholas Hopper (professor)

Artificial Intelligence & Cooperation [preprint]
Posted December 10, 2020
Elisa Bertino, Finale Doshi-Velez, Maria Gini (professor), Daniel Lopresti, David Parkes

A Generative Approach for Detection-driven Underwater Image Enhancement [preprint]
Posted December 10, 2020
Chelsey Edge (Ph.D. student), Md Jahidul Islam (Ph.D. student), Christopher Morse (undergraduate research assistant), Junaed Sattar (assistant professor)
More About Research areas
- Architectures, Compiler Optimization, and Embedded Systems
- Data Mining, Databases, and Geographical Information Systems
- Graphics and Immersive Computing
- High Performance Computing
- Human Computer Interaction (HCI)
- Networks, Distributed Systems, and Security
- Robotics and Artificial Intelligence
- Software Engineering and Programming Languages
- Theoretical Foundations