Latest research projects, publications, and talks
Identification and characterization of a fungal-selective glutaminyl tRNA synthetase inhibitor with potent activity against Candida albicans [journal]
Posted
Alice Xue, Amanda Veri, Xiang Zhang, Ci Fu, Emma Lash, Kali Iyer, Nicole Revie, Nicole Robbins, Charles Boone, Chad Myers (professor), Leah Cowen
Access Microbiology
Probing ion channel functional architecture and domain recombination compatibility by massively parallel domain insertion profiling [journal]
Posted
Willow Coyote-Maestas, David Nedrud, Antonio Suma, Yungui He, Kenneth A Matreyek, Douglas M Fowler, Vincenzo Carnevale, Chad L Myers (professor), Daniel Schmidt
Nature Communications
Microbiome based systems, apparatus and methods for monitoring and controlling industrial processes and systems [patent]
Posted
Rob Knight, Ajay Kshatriya, Chris Lauber, J Gregory Caporaso, Dan Knights (professor), Ryan Gill, Joel Moxley
Participatory Microbiome Research With Hmong and Karen Communities: Lessons Learned [journal]
Posted
Pajau Vangay, Nancy Yang, Shannon Pergament, Mary Xiong, Bwei Paw, Rodolfo Batres, Dan Knights (professor), Kathleen A Culhane-Pera
Journal of Participatory Research Methods
Leveraging machine learning essentiality predictions and chemogenomic interactions to identify antifungal targets [journal]
Posted
Ci Fu, Xiang Zhang (Ph.D. student), Amanda O Veri, Kali R Iyer, Emma Lash, Alice Xue, Huijuan Yan, Nicole M Revie, Cassandra Wong, Zhen-Yuan Lin, Elizabeth J Polvi, Sean D Liston, Benjamin VanderSluis (Ph.D. 2014), Jing Hou, Yoko Yashiroda, Anne-Claude Gingras, Charles Boone, Teresa R O’Meara, Matthew J O’Meara, Suzanne Noble, Nicole Robbins, Chad L Myers (professor), Leah E Cowen
Nature Communications
Multi-omics analyses show disease, diet, and transcriptome interactions with the virome [journal]
Posted
Kathie A Mihindukulasuriya, Ruben AT Mars, Abigail J Johnson, Tonya Ward, Sambhawa Priya, Heather R Lekatz, Krishna R Kalari, Lindsay Droit, Tenghao Zheng, Ran Blekhman, Mauro D’Amato, Gianrico Farrugia, Dan Knights (professor), Scott A Handley, Purna C Kashyap
Gastroenterology
Heuristic and Hierarchical-Based Population Mining of Salmonella enterica Lineage I Pan-Genomes as a Platform to Enhance Food Safety [journal]
Posted
Joao Carlos Gomes-Neto, Natasha Pavlovikj, Carmen Cano, Baha Abdalhamid, Gabriel Asad Al-Ghalith, John Dustin Loy, Dan Knights (professor), Peter C Iwen, Byron D Chaves, Andrew K Benson
Frontiers in Sustainable Food Systems
Analysis of combinatorial CRISPR screens with the Orthrus scoring pipeline [journal]
Posted
Henry N Ward (Ph.D. student), Michael Aregger, Thomas Gonatopoulos-Pournatzis, Maximilian Billmann (postdoctoral associate), Toshiro K Ohsumi, Kevin R Brown, Benjamin J Blencowe, Jason Moffat, Chad L Myers (professor)
Nature Protocols
Improving Measures of Chemical Structural Similarity Using Machine Learning on Chemical–Genetic Interactions [journal]
Posted
Hamid Safizadeh (Ph.D. student), Scott W Simpkins (Ph.D. 2018), Justin Nelson (Ph.D. 2019), Sheena C Li, Jeff S Piotrowski, Mami Yoshimura, Yoko Yashiroda, Hiroyuki Hirano, Hiroyuki Osada, Minoru Yoshida, Charles Boone, Chad L Myers (professor)
Journal of Chemical Information and Modeling
Association of BMI, comorbidities and all-cause mortality by using a baseline mortality risk model [journal]
Posted
Jia Li (M.S. 2020), Gyorgy Simon, M Regina Castro, Vipin Kumar (professor), Michael S Steinbach (researcher), Pedro J Caraballo
PLOS ONE