Allison Hubel

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Allison Hubel

Professor,
Mechanical Engineering

Contact

Mechanical Engineering
Rm 2101C
111 Church Street SE

Minneapolis,

MN

55455

Affiliations

Director, BioCor
Education

Ph.D. M.S., Mechanical Engineering, 
Massachusetts Institute of Technology 

B.S., Mechanical Engineering,
Iowa State University

Research Interests
  • Molecular mechanisms of damage during freezing
  • Mechanisms of cryoprotection or cryoinjury
  • Low temperature imaging of biological systems
  • Preservation of cells and tissues
  • Microfluidics and transport in microfluidic channels

Research Groups

BioCor - Biopreservation Core Research

Hubel Research Group

 

Honors and Awards
  • 2017 Outstanding Achievement in Biobanking, ISBER
  • 2013 Scholar, National Blood Foundation
  • 2012 Fellow, American Institute of Medical and Biological Engineers
  • 2008 Fellow, American Society of Mechanical Engineers
  • 2001 Presidential Distinguished Faculty
Selected Publications
  • Pollock K, Budenske JW, McKenna DH, Dosa PI, Hubel A, “Algorithm-driven optimization of cryopreservation protocols,” J Tissue Engr Regen Med, 10: 2806-2815, 2017
  • Pollock K, Samsonraj RM, Dudakovic A, Thaler R, Stumbras A, McKenna DH, Dosa PI, van Wijnen AJ, Hubel A, “Improved post-thaw function and epigenetic changes in mesenchymal stromal cells cryopreserved using multicomponent osmolyte solutions,” Stem Cells and Development, 26: 828-842, 2017.
  • Yu G, Pollock K, Yap YR, Hubel A, “Characterizing intracellular ice formation of lymphoblasts cryopreserved in different cryoprotectant compositions using low temperature Raman microspectroscopy,” Biophysical J, 112 (12): 2653-2663, 2017.
  • Pi C.H., Yu G, Petersen A, Hubel A, “Characterizing the ‘Sweet spot” for the preservation of a T-cell line using osmolytes”, Scientific Reports, 8(1): p. 16223, 2018.
  • Yu G, Li R, Hubel A, “Interfacial interactions of sucrose during cryopreservation detected by Raman spectroscopy”, Langmuir, DOI: 10.1021/acs.langmuir.8b01616, 2018.

See a full list of publications here.