Bringing AI to Healthcare – Application of Large Language Models to Interpret Complex Microbiome Data

Industrial Problems Seminar 

Leo Grady (Jona)

Abstract

For the first time, Large Language Models (a form of AI) can draw together the entirety of both the medical literature and the scientific literature to create a generative interpretation of a person’s health data with the latest knowledge to guide personalized health understanding and action. This interpretation is essential for the gut microbiome because microbiome data is especially complex and the literature is fast moving. The microbiome has been demonstrated to broadly underpin human health from digestive disorders and autoimmune disease to obesity, cancer, drug efficacy, liver disease, human longevity, Parkinson’s Disease and even mental health. Yet, so far the microbiome has been too complex and the science too fast moving to benefit individuals, doctors and innovators in practice. Jona is a technology company that has built a proprietary AI system to read a person’s microbiome levels and summarize the scientific literature linking their microbiome to signatures found to be associated with different diseases, conditions, symptoms and allergies. Jona provides a measure of the strength of evidence for each association, as well as links to all the supporting studies. In addition, Jona’s AI system summarizes how to take action from these results by identifying those actions studied in the literature that impact your specific microbiome in ways that can improve your health.