Matthew Tirrell

Amundson Distinguished Professor

Contact

tirrell@umn.edu

612/625-0469

331 Amundson Hall
421 Washington Avenue SE
Minneapolis, MN 55455

Matthew Tirrell

Amundson Distinguished Professor

Research

Research Interests

Complexation of charged macromolecules has been employed for decades to produce encapsulating materials, up to and including materials used in contemporary e-readers, to keep particles in a fine state of dispersion. Especially interesting is when such macromolecules undergo liquid-liquid phase separation creating fluid droplets with very low interfacial tension with water. Such droplets have been implicated as protocells in origin of life discussions and are increasingly being discovered as intracellular compartments, membraneless organelles and condensates in biology with a variety of functional properties.

Our work of the last few years has been focused on quantitative understanding of the polymer physics of polyelectrolyte complexation. We have published the first phase diagram of a polyelectrolyte complex undergoing phase separation, without employing any simplifying assumptions [“Phase behavior and salt partitioning in polyelectrolyte complex coacervates”, L. Li, S. Srivastava, M. Andreev, A.B. Marciel, J.J. dePablo and M. Tirrell, Macromolecules, 51, 2988-2995 (2018)]. We have demonstrated that complexation with nucleic acids depends on the state of hybridization [“Oligonucleotide–Peptide Complexes: Phase Control by Hybridization”, J. R. Vieregg, M. Lueckheide, A. B. Marciel, L. Leon, A. J. Bologna, J. R. Rivera, M. Tirrell, J. Am. Chem. Soc., 140, 1632–1638 (2018)]. We have provided the first evidence of positional charge correlation in liquid polyelectrolyte complexes. [“Scattering evidence of positional charge correlations in polyelectrolyte complexes”, Y.N. Fang, A.M. Rumyantsev, A.E.Neitzel, Y. Liang, W.T. Heller, P.F. Nealey, M. Tirrell, J.J. dePablo, PNAS, 120, e2302151120 (2023)]. We have also demonstrated that complexation can be used for creating new self-assembled structures.[ “Structure-Property Relationships of Oligonucleotide Polyelectrolyte Complex Micelles”, M. Lueckheide, J.R. Vieregg, A.J. Bologna, L. Leon and M. Tirrell, Nano Letters, 18, 7111-7117 (2018)]. Work along these lines continues.

Our work also exploits these novel self-assembly properties to create delivery vehicles for therapeutic nucleic acids in vivo with a particular focus on cardiovascular disease [“Targeted polyelectrolyte complex micelles treat vascular complications in vivo”, Zhou, Z., Yeh, C.-F., Mellas, M., Oh, M.-J., Zhu, J., Li, J., Huang, R.-T., Harrison, D., Shentu, T.-P., Wu, D., Lueckheide, M., Carver L., Chung, E.J., Leon, L., Yang, K.-C., Tirrell, M.V., Fang, Y, PNAS, 118, e2114842118 (2021).]. This paper demonstrated that these nanoparticles can retard the progression of atherosclerosis, and can reduce the occlusion of blood vessels that often develops due to disturbed blood flow in the implantation of stents and in arteriovenous fistulas performed on kidney dialysis patients.

Biography

Publications & Awards

Honors and Awards

1980 Camille and Henry Dreyfus Teacher-Scholar Award
1982 Alfred P. Sloan Foundation Fellowship
1984 NSF Presidential Young Investigator Award
1985 Allan P. Colburn Award, American Institute of Chemical Engineers
1986 John Simon Guggenheim Memorial Foundation Fellowship
1987 John H. Dillon Medal, American Physical Society
1987 Chancellor's Medal, University of Massachusetts at Amherst
1987 Fellow, American Physical Society
1994 Professional Progress Award, American Institute of Chemical Engineers
1996 Charles M. A. Stine Award, American Institute of Chemical Engineers
1997 National Academy of Engineering
2000 Fellow, American Institute of Medical and Biological Engineering
2000 Fellow, American Association for the Advancement of Science
2001 Institute Lecturer, American Institute of Chemical Engineers
2005 Le Prix Dédale de la Sociéte Française d’Adhesion
2004 NSF Engineering Distinguished Lecture
2004 Honorary Fellow of the Institute of Chemical Engineers U.K.(IChemE)
2004 Danckwerts Lecture, European Society of Chemical Engineers
2007 William H. Walker Award, American Institute of Chemical Engineers
2008 Fellow, Indian National Academy of Engineering
2009 Fellow, American Academy of Arts & Sciences
2010 Chevalier dans l’Order des Palmes Académiques, Ministry of Education of France
2012 Polymer Physics Prize, American Physical Society
2019 National Academy of Sciences
2019 Docteur Honoris Causa, Université de Bordeaux
2022 National Award in Colloid Chemistry, American Chemical Society

Special Lectures

1984 Allan P. Colburn Lecturer, University of Delaware
1985 Robert W. Vaughan Lecturer, California Institute of Technology
1991 Olaf A. Hougen Professor of Chemical Engineering, University of Wisconsin
1991 Nieuwland Lecturer in Chemistry, University of Notre Dame
1991 Dow Lecture in Polymer Science, University of Massachusetts
1992 Ashton Cary Lectures, Georgia Institute of Technology
1992 Donald Katz Lectures, University of Michigan
1993 Merck Sponsored Distinguished Lectures, Rutgers University
1994 Julian Smith Lecturer, Cornell University
1995 Berkeley Lecturer in Chemical Engineering, University of California
1995 Warren K. Lewis Lectures, Massachusetts Institute of Technology
1997 Madden Lecture, University of Pennsylvania
1997 G.S. Whitby Lectures, University of Akron
1997 Joseph Smith Distinguished Lecturer, University of California, Davis
1998 Rohm and Haas Lectures, University of North Carolina
1998 Kelly Lectures, Purdue University
1998 Mason Lectures, Stanford University
1999 Chancellor’s Distinguished Lecturer, Louisiana State University
2000 Stanley Katz Memorial Lecture, City College of New York
2001 Distinguished Patten Lecturer, University of Colorado
2003 Aggarwal Lectures, Cornell University
2003 Centennial Lecturer, Ohio State University
2003 Leland Lecture, Rice University
2003 Turner Alfrey Lectures, Michigan Molecular Institute
2004 W.N. Lacey Lecturer, California Institute of Technology
2005 NSF Engineering Division Distinguished Lecture
2005 ICI Distinguished Lectures, University of Alberta
2005 NSF Engineering Distinguished Lecture
2008 Corneilius Pings Lecture, University of Southern California
2010 Distinguished Lecture in Chemical Engineering, Imperial College, London
2010 Carlton Society Lecturer, 3M Corporation
2011 Alumni Lectures in Chemical Engineering, University of Massachusetts
2011 Centennial Lecture, IBM
2013 Reilly Lectures, Notre Dame University
2013 Distinguished Chemical Engineering Seminar: The Leaders’ Forum, Imperial College, London
2013 Eastman Lectures in Polymer Science and Engineering, University of Akron
2017 Wilhelm Lectures, Princeton University
2017 Institute for Molecular Science and Engineering Highlight Seminar, Imperial College, London
2017 Covestro Lectures, University of Pittsburgh
2018 Lowrie Lectures, The Ohio State University
2019 Grodins Lecture, University of Southern California
2019 Millipore Sigma Aldrich Lecture, University of Washington
2020 Alumni Lecture, Northwestern University
2023 Joe L. Franklin Memorial Lecture, Rice University

Selected Publications

374. “Peptide amphiphile micelles for vaccine delivery”, J.C. Barrett and M. Tirrell, Methods in Molecular Biology, 1798, 277-292
(2018). DOI: 10.1007/978-1-4939-7893-9_21
375. “A zwittwerionic block-copolymer, based on glutamic acid and lysine, reduces the biofouling of UF and RO membranes”, M.
Piatkovsky, H. Acar, A.B. Marciel, M. Tirrell and M. Herzberg, J. Membrane Sci., 549, 507-514 (2018). DOI:
10.1016/j.memsci.2017.12.042
376. “Open-to-Air RAFT Polymerization in Complex Solvents: From Whisky to Fermentation Broth”, D.K. Schneiderman, J.M.
Ting, A.A. Purchel, R. Miranda, M. Tirrell, T.M. Reineke and S.J. Rowan, ACS Macro Letters, 7, 406-411 (2018). DOI:
10.1021/acsmacrolett.8b00069
377. “Structure and rheology of polyelectrolyte complex coacervates”, A.B. Marciel, S. Srivastava and M. Tirrell, Soft Matter, 14,
2454-2464 (2018). DOI: 10.1039/c7sm02041d
378. “Antifouling properties of a self-assembling glutamic acid – lysine zwitterionic polymer surface coating”, C. Ziemba, M.
Khavkin, D. Priftis, H. Acar, J. Mao, M. Benami, M. Gottlieb, M. Tirrell, Y. Kaufman and M. Herzberg, Langmuir, 35,
1699-1713 (2018). DOI:10.1021/acs.langmuir.8b0018
379. “Phase behavior and salt partitioning in polyelectrolyte complex coacervates”, L. Li, S. Srivastava, M. Andreev, A.B. Marciel,
J.J. dePablo and M. Tirrell, Macromolecules, 51, 2988-2995 (2018). DOI: 10.1021/acs.macromol.8b00238
380. “Polyelectrolyte Complexes: Fluid or Solid?”, M. Tirrell, ACS Central Science, 4, 532-533 (2018). DOI:
10.1021/acscentsci.8b00284
381. “Synthesis and Assembly of Designer Styrenic Diblock Polyelectrolytes”, J.M. Ting, H. Wu, A. Herzog-Arbeitman, S. Srivastava
and M. Tirrell, ACS Macro Letters, 7, 726-733 (2018). DOI: 10.1021/acsmacrolett.8b00346
382. “Multivalent counterions diminish the lubricity of polyelectrolyte brushes”, J. Yu, N. E. Jackson, X. Xu, Y. Morgenstern, Y.
Kaufman, M. Ruths, J. J. de Pablo, M. Tirrell, Science, 360, 1434–1438 (2018). DOI: 10.1126/science.aar5877
383. “Polymers at the interface with biology”, T.J. Deming, H.-A. Klok, S.P. Armes, M.L. Becker, J.A. Champion, E.Y.X. Chen,
S.C. Heilshorn, J.C.M. van Hest, D.J. Irvine, J.A. Johnson, L.L. Kiessling, H.D. Maynard, M.O. Olvera de la Cruz, M.O.
Sullivan, M. Tirrell, K.S. Anseth, S. Lecommandoux, S. Percec, Z.Y. Zhong and A.C. Albersson, Biomacromolecules, 19,
3151-3162 (2018). DOI: 10.1021/acs.biomac.8b01029
384. “Complex coacervation in polyelectrolytes from a coarse-grained model”, M. Andreev, V.M. Prabhu, J.F. Douglas, M. Tirrell
and J.J. de Pablo, Macromolecules, 51, 6717-6723 (2018). DOI: 10.1021/acs.macromol.8b00556
385. “Synthesis and purification of homogeneous, lipid-based, peptide nanocarriers by overcoming phospholipid ester hydrolysis”,
M.R. Schnorenberg, S.P. Yoo, M. Tirrell and J.L. LaBelle, ACS Omega, 3, 14144-14150 (2018). DOI:
10.1021/acsomega.8b01772
386. “Non-equilibrium phenomena and kinetic pathways in self-assembled polyelectrolyte complexes”, H. Wu, J.M. Ting, O. Werba,
S.Q. Meng and M. Tirrell, J. Chem. Phys., 149, Article Number: 163330 (2018). DOI: 10.1063/1.5039621
387. “Effect of temperature on the structure and dynamics of triblock polyelectrolyte gels”, A. Rahalkar, G. Wei, R. Nieuwendall,
V.M. Prabhu, S. Srivastava, A.E. Levi, J.J. de Pablo and M. Tirrell, J. Chem. Phys., 149, Article Number: 163310 (2018). DOI:
10.1063/1.5035083
388. “Structure-Property Relationships of Oligonucleotide Polyelectrolyte Complex Micelles”, M. Lueckheide, J.R. Vieregg, A.J.
Bologna, L. Leon and M. Tirrell, Nano Letters, 18, 7111-7117 (2018). DOI: 10.1021/acs.nanolett.8b03132
389. “Polyelectrolyte complexation of oligonucleotides by charged hydrophobic neutral hydrophilic block copolymers”, A. Marras,
J.R. Vieregg, J.M. Ting, J.D. Rubien and M.V. Tirrell, Polymers, 11, Article Number: 83 (2019).
390. “A pH-triggered, self-assembled, and bioprintable hybrid hydrogel scaffold for mesenchymal stem cell-based bone tissue
engineering”, C. Zhao, N.T. Qazvini, M. Sadati, Z. Zeng, S. Huang, A.L. de la Lastra, L. Zheng, F. Linghuan, W. Liu, B. Huang,
B. Zhang, Z. Dai, Y. Shen, X. Wang, W. Luo, B. Liu, Y. Lei, Z. Ye, C. Ling, D. Cao, L. Yang, X. Chen, A. Athiviraham, M.J.
Lee, J.M. Wolf, R.R. Reed, M. Tirrell, J.J. de Pablo and T.-C. He, ACS Applied Materials and Interfaces, 11, 8749-8762 (2019).
391. "Interparticle Interactions in Dilute Solutions of Polyelectrolyte Complex Micelles", Wu, Hao, Jeffrey M. Ting, Thomas M.
Weiss and Matthew V. Tirrell, ACS Macro Letters, 8, 819-825 (2019).
392. Activating the Intrinsic Pathway of Apoptosis Using BIM BH3 Peptides Delivered by Peptide Amphiphiles with Endosomal
Release”, Schnorenberg, M.R., Bellairs, J.A., Samaeekia, R., Acar, H., Tirrell, M.V. and LaBelle, J.L., Materials 12, 2567
(2019).
393. “Ion-Specific Effects of Divalent Ions on the Structure of Polyelectrolyte Brushes”, Xin Xu, Dean Mastropietro, Marina Ruths,
Matthew Tirrell,and Jing Yu, Langmuir, 35, 15564-15572 (2019).
394. "Controlling complex coacervation via random polyelectrolyte sequences", Rumyantsev, Artem M., Nicholas E. Jackson, Boyuan
Yu, Jeffrey M. Ting, Wei Chen, Matthew V. Tirrell and Juan J. de Pablo. ACS Macro Letters 8, 1296-1302 (2019).
395. "Integrating Systems Thinking into Teaching Emerging Technologies", Whitney C. Fowler, Jeffrey M. Ting, Siqi Meng, Lu Li
and Matthew V. Tirrell. Journal of Chemical Education 96, 2805-2813 (2019)
396. "Preferential targeting of MCL-1 by a hydrocarbon-stapled BIM BH3 peptide", Hadji, Abbas, Greta K. Schmitt, Mathew R.
Schnorenberg, Lauren Roach, Connie M. Hickey, Logan B. Leak, Matthew V. Tirrell and James L. LaBelle. Oncotarget 10,
6219-6225 (2019).
397. "Enrichment and Distribution of Pb2+ Ions in Zwitterionic Poly (cysteine methacrylate) Brushes at the Solid-Liquid Interface",
He, Qiming, Yijun Qiao, David J. Mandia, Shenglong Gan, Huiru Zhang, Hua Zhou, Jeffrey W. Elam, Seth B. Darling, Matthew
V. Tirrell and Wei Chen. Langmuir, 35, 17082–17089 (2019).
398. “Structure and dynamics of lipid membranes interacting with antivirulence end-phosphorylated polyethylene glycol block
copolymers”, Yu, J., Mao, J., Nagao, M., Bu, W., Lin, B., Hong, K., Jiang, Z., Liu, Y., Qian, S., Tirrell, M. and Chen, W. Soft
Matter, 16, 983-989 (2020)
399. “Hydrophobically assembled nanoparticles: Self-assembled nanoparticles”, Wang, J., Mellas, M., Tirrell, M. and Chung, E.J.,
2020. In Nanoparticles for Biomedical Applications (pp. 325-347). Elsevier. DOI: 10.1016/B978-0-12-816662-8.00019-9
400. "Mechanism of Dissociation Kinetics in Polyelectrolyte Complex Micelles", Wu, H., Ting J.M., and Tirrell, M.V.,
Macromolecules, 53, 102-111 (2020).
401. "An in situ shearing x-ray measurement system for exploring structures and dynamics at the solid–liquid interface", Qiao, Yijun,
Hua Zhou, Zhang Jiang, Qiming He, Shenglong Gan, Hongdong Wang, Shizhu Wen, Wei Chen and M. Tirrell, Review of
Scientific Instruments 91, 013908 (2020)
402. “Assembly and Characterization of Polyelectrolyte Complex Micelles”, Marras, A. E., Vieregg, J. R. and Tirrell, M. V. J. Vis.
Exp. 157, e60894, (2020)
403. “Effect of mixed solvents on polyelectrolyte complexes with salt. Effect of mixed solvents on polyelectrolyte complexes with
salt”, Meng, S., Liu, Y., Yeo, J., Ting, J. M., and Tirrell, M. V. Colloid Polym Sci 298, 887–894 (2020).
404. “Solid-to-Liquid Phase Transition in Polyelectrolyte Complexes”, S. Meng, J. M. Ting, H. Wu and M.V. Tirrell.
Macromolecules, 53, 7944-7953 (2020).
405. “Effects of Non-Electrostatic Intermolecular Interactions on the Phase Behavior of pH-Sensitive Polyelectrolyte Complexes”, L.
Li, S. Srivastava, S. Meng, J. M. Ting and M. V. Tirrell. Macromolecules, 53, 7835-7844 (2020).
406. “Structure, Morphology, and Rheology of Polyelectrolyte Complex Hydrogels Formed by Self-Assembly of Oppositely Charged
Triblock Polyelectrolytes”, S. Srivastava, A. E. Levi, D. J. Goldfeld and M. V. Tirrell. Macromolecules, 53, 5763-5774 (2020)
407. “Comparing Zwitterionic and PEG Exteriors of Polyelectrolyte Complex Micelles”, J. M. Ting, A. Marras, J. D. Mitchell, T. R.
Campagna and M. V. Tirrell, Molecules, 25, 2553-2570 (2020).
408. “Impact of wet-dry cycling on the phase behavior and compartmentalization properties of complex coacervates”, Fares, H.M.,
Marras, A.E., Ting, J.M., Tirrell, M.V. and Keating C.D., Nature Communications 11, article number: 5423 (2020).
409. “Spatiotemporal Formation and Growth Kinetics of Polyelectrolyte Complex Micelles with Millisecond Resolution”, Wu, H.,
Ting, J. M., Yu, B.Y., Meng, S., de Pablo, J.J. and Tirrell, M., ACS Macro Letters, 9, 1674-1680 (2020).
410. "Effect of Solvent Quality on the Phase Behavior of Polyelectrolyte Complexes", Li, L., Rumyantsev, A., Srivastava, S., Meng,
S., de Pablo, J.J. and Tirrell, M., Macromolecules, 54, 105-114 (2021).
411. "SAXS methods for investigating macromolecular and self-assembled polyelectrolyte complexes", Marciel, A.B., Srivastava, S.,
Ting, J.M. and Tirrell, M., Methods in Enzymology, 646, 223-259 (2021).
412. “Protein primary structure correlates with calcium oxalate stone matrix preference”, Tian, Y., Tirrell, M., Davis, C. and Wesson,
J.A., PLOS ONE, 16, e0257515 (2021).
413. “Harnessing Peptide Binding to Capture and Reclaim Phosphate”, Fowler, W.C., Deng, C.T., Griffen, G.M., Teodoro, T., Guo,
A.Z., Zaiden, M., Gottlieb, M., de Pablo, J.J. and Tirrell, M.V., JACS, 143, 4440-4450 (2021).
414. “Expanding the structural diversity of polyelectrolyte complexes and polyzwitterions”, Neitzel, A.E., De Hoe, G.X. and Tirrell,
M.V., Current Opinion in Solid State & Materials Science, 25, 100897 (2021)
415. “Advances in the Structural Design of Polyelectrolyte Complex Micelles”, Marras, A.E., Ting, J.M., Stevens, K.C. and Tirrell,
M.V., J. Phys. Chem., B, 125, 7076-7089 (2021).
416. “Physical Property Scaling Relationships for Polyelectrolyte Complex Micelles”, Marras, A.E., Campagna, T.R., Vieregg, J.R.
and Tirrell, M.V., Macromolecules, 54, 6585-6594 (2021).
417. “Polyelectrolyte Complex Coacervation across a Broad Range of Charge Densities”, Neitzel, A.E., Fang, Y.N., Yu, B.Y.,
Rumyantsev, A., de Pablo, J.J. and Tirrell, M., Macromolecules, 54, 6878-6890 (2021).
418. “Complex coacervation of statistical polyelectrolytes: role of monomer sequences and formation of inhomogeneous coacervates”,
Yu, B.Y., Rumyantsev, A., Jackson, N.E., Liang, H.Y., Ting, J.M., Meng, S., Tirrell, M. and de Pablo, J.J., Molecular Systems
Design & Engineering, 6, 790-804 (2021).
419. “Advanced Materials for Energy-Water Systems: The Central Role of Water/Solid Interfaces in Adsorption, Reactivity, and
Transport”, Darling, S.B., et al (40 co-authors), Chem. Rev., 121, 9450–9501 (2021).
420. “Polymersomes Decorated with the SARS-CoV-2 Spike Protein Receptor-Binding Domain Elicit Robust Humoral and Cellular
Immunity”, Volpatti, L.R., et al, (30 co-authors), ACS Central Science, 7, 1368-1380 (2021).
421. “Nanometer-Scale Force Profiles of Short Single- and Double-Stranded DNA Molecules on a Gold Surface Measured Using a
Surface Forces Apparatus”, Kang, D., Yu, J., Xia, F., Huang, J., Zeng, H., Tirrell, M., Israelachvili, J., and Plaxco, K.W.,
Langmuir, 37, 13346-13352 (2021).
422. “Targeted polyelectrolyte complex micelles treat vascular complications in vivo”, Zhou, Z., Yeh, C.-F., Mellas, M., Oh, M.-J.,
Zhu, J., Li, J., Huang, R.-T., Harrison, D., Shentu, T.-P., Wu, D., Lueckheide, M., Carver L., Chung, E.J., Leon, L., Yang, K.-C.,
Tirrell, M.V., Fang, Y, PNAS, 118, e2114842118 (2021).
423. “Polymorphism in Peptide Self-Assembly Visualized”, Tirrell, M., PNAS, 119, e2123197119 (2022). Invited Commentary on
article by Pieri, et al.
424. “Harnessing the Therapeutic Potential of Biomacromolecules through Intracellular Delivery of Nucleic Acids, Peptides, and
Proteins”, Tian, Y., Tirrell, M.V., LaBelle, J.L., Advanced Healthcare Materials, 11, 2102600 (2022).
425. “Translocation Behaviors of Synthetic Polyelectrolytes through Alpha-Hemolysin (alpha-HL) and Mycobacterium smegmatis
Porin A (MspA) Nanopores”, Wang, X.-Q., Stevens, K.C., Ting, J.M., Marras, A.E., Rezvan, G., Wei, X.-J., Taheri-Qazvini, N.,
Tirrell, M.V., Liu, C., J. Electrochem. Soc., 169, 057510 (2022).
426. “Parameter estimation for X-ray scattering analysis with Hamiltonian Markov Chain Monte Carlo”, Jiang, Z., Wang, J., Tirrell,
M.V., de Pablo, J.J., Chen, W., J. Synchrotron Radiation, 29, 721-731 (2022).
427. “Manipulation of coacervate droplets with an electric field”, Agrawal, Aman; Douglas, Jack F; Tirrell, Matthew; Karim, Alamgir,
PNAS, 119, e2203483119 (2022).
428. “Sequence-Controlled Secondary Structures and Stimuli Responsiveness of Bioinspired Polyampholytes”, Dinic, Jelena;
Schnorenberg, Mathew; Tirrell, Matthew, Biomacromolecules, 23, 3798-3809 (2022).
429. “Liquid capsules for gastrointestinal drug delivery”, Lui, J.H.; Perry, S.L.; Tang, B.Z.; Tirrell, M., Matter, 5, 3107-3109 (2022).
430. “Inhibition of FOXP3 by stapled alpha-helical peptides dampens regulatory T cell function”, Hawley, Katrina M.; Eclov, Rachel
J.; Schnorenberg, Mathew R.; Tian, Yu; Shah, Rhea N.; Fefferman, Marie; Bird, Gregory H.; Walensky, Loren D.; Tirrell,
Matthew V.; LaBelle, James L., PNAS, 119, e2209044119 (2022).
431. “Ion Specificity Influences on the Structure of Zwitterionic Brushes”, Qiming He, Yijun Qiao, Carlos Medina Jimenez, Ryan
Hackler, Alex B. F. Martinson, Wei Chen, Matthew Tirrell, Macromolecules, 56, 1945–1953 (2023).
432. “Effect of Charged Block Length Mismatch on Double Diblock Polyelectrolyte Complex Micelle Cores”, K. C. Stevens, A.E.
Marras, T. R. Campagna, J. M. Ting, M. Tirrell, Macromolecules, 56, 5557–5566 (2023).
433. “Scattering evidence of positional charge correlations in polyelectrolyte complexes”, Fang, Yan N, Rumyantsev, Artem M,
Neitzel, Angelika E, Liang, Heyi, Heller, William T, Nealey, Paul F, Tirrell, Matthew V, de Pablo, Juan J., PNAS, 120,
e2302151120 (2023).
434. "Targeted polymersome delivery of a stapled peptide for drugging the p53:BCL-2-family axis in diffuse large B-cell lymphoma",
Schnorenberg, Mathew, Hawley, Katrina, Thomas-Toth, Anika, Watkins, Elyse, Tian, Yu, Ting, Jeffrey, Leak, Logan, Kucera,
Isadora, Raczy, Michal, Kung, Andrew, Hubbell, Jeffrey, Tirrell, Matthew, LaBelle, James, ACS Nano, in press (2023).
435. “Structure and Dynamics of Hybrid Colloid–Polyelectrolyte Coacervates: Insights from Molecular Simulations”, Boyuan Yu,
Heyi Liang, Paul F. Nealey, Matthew V. Tirrell, Artem M. Rumyantsev, Juan J. de Pablo, Macromolecules, in press (2023).