Jochen Mueller

A man wearing a pink shirt and glasses

Jochen Mueller

Professor, School of Physics and Astronomy


Physics And Nanotechnology Building
Room 418
115 Union St. Se
Minneapolis, MN 55455


Ph.D., Technical University of Munich, 1997 

Professional Background

Member of the Graduate Research Advisory Committee (GRAC), Graduate School, University of Minnesota, Spring 2006-present

Organizer of Annual Hands-On Fluorescence Workshop for Students of Biological Sciences, 2006-2010

Panel Member, Biological Physics Review, NSF, 2006

Session Chair, 6th International Weber Symposium on Innovative Fluorescence Methodologies in Biochemistry and Medicine, 2005

Member, “Single cell / Single molecule” focus group as part of CBISC (Steering Committee of the Chemical Biology Initiative, 2004

Panel Member, MPS-MCB Review, NSF, 2004

Session Chair, 5th International Weber Symposium on Innovative Fluorescence Methodologies in Biochemistry and Medicine, 2002

Research Interests

Experimental biophysics, Two-photon excitation microscopy, Fluorescence fluctuation spectroscopy

Selected Publications

J. P. Skinner, Y. Chen, and J. D. Mueller, Fluorescence Fluctuation Spectroscopy in the Presence of Immobile Fluorophores,", Biophys J (2008)

B. Wu, Y. Chen, and J. D. Mueller, Fluorescence Correlation Spectroscopy of Finite-Size Particles,”, Biophys J (2008)

B. P. Duckworth, Y. Chen, Y. Sham, J. D. Mueller, T. A. Taton, and M. D. Distefano, A Universal Method for the Preparation of Covalent Protein-DNA Conjugates for Use in Creating Protein Nanostructures,", Chem., Int. Ed.(2007)

Y. Chen and J. D. Müller, Determining the Stoichiometry of Protein Hetero-complexes in Living Cells with Fluorescence Fluctuation Spectroscopy,", Proc. Natl. Acad. Sci. USA (2007)

L. N. Hillesheim, Y. Chen, and J. D. Mueller, Dual-Color Photon Counting Histogram Analysis of mRFP1 and EGFP in Living Cells,", Biophys J (2006)

Y. Chen, M. Tekmen, L. N. Hillesheim, J. Skinner, B. Wu, and J. D. Müller, Dual-Color Photon Counting Histogram, Biophys. J. (accepted) 2005

M. Tekmen and J. D. Müller, High-Pressure Cell for Fluorescence Fluctuation Spectroscopy, Rev. Sci. Instr., 75, 5143-5148 (2004).

J. D. Müller, M. Tekmen, L. N. Hillesheim, W. Yang, and Y. Chen, Dual-Color Fluorescence Fluctuation Spectroscopy in vitro and in vivo, SPIE Proc. 5323, 136-145 (2004).

J. D. Müller, Cumulant analysis in fluorescence fluctuation spectroscopy, Biophys. J. 86(6), 3981-3992 (2004).

Y. Chen, L. N. Wei, and J. D. Müller , Probing protein oligomerization in living cells with fluorescence fluctuation spectroscopy, Proc. Natl. Acad. Sci. USA 100(26), 15492-15497 (2003).

L. N. Hillesheim and J. D. Müller, The Photon Counting Histogram in Fluorescence Fluctuation Spectroscopy with Non-ideal Photodectors, Biophys. J. 85, 1948-1958 (2003).

J. D. Müller, Following protein association in vivo with fluorescence fluctuation spectroscopy, SPIE Proc. 4963, 24-31 (2003).

J. D. Müller and E. Gratton, High-Pressure Fluorescence Correlation Spectroscopy, Biophys. J. 85(4), 2711-2719 (2003).