They
Associate Professor, Department of Biomedical Engineering
Contact
Room 6-126 Nils Hasselmo Hall
312 Church St SE
Minneapolis, MN 55455
They
Associate Professor, Department of Biomedical Engineering
Shai Ashkenazi's research lab — the Ultrasound, Photoacoustic and Optoacoustic Lab (UPOL) — explores ways to develop high-resolution imaging devices and new functional imaging techniques by combining laser, fiber optics, and ultrasound technologies.
This route has led us to developing a unique method for non-invasive imaging of tissue oxygen. We investigate how this new imaging modality can help in improving outcomes of cancer therapy.
In other projects, we build optical fiber based devices that can receive and transmit ultrasound and communicate signals optically. Such technology can enable miniaturization of imaging devices to allow precise guiding of cardiovascular interventions.
S. –W. Huang, S. –L. Chen, T. Ling, A. Maxwell, L. J. Guo, and S. Ashkenazi, “Low-noise wideband ultrasound detection using polymer microring resonators”, Accepted for publication in Applied Physics Letters (Apr. 2008).
T. D. Horvath, G. Kim, R. Kopelman, and S. Ashkenazi, “Ratiometric Photoacoustic Sensing of pH using a Sonophore”, accepted for publication in The Analyst (2008).
S. Ashkenazi, S.-W. Huang, T. Horvath, Y. –E. L. Koo, and R. Kopelman, “Photoacoustic probing of fluorophore excited state lifetime with application to oxygen sensing”, J. of Biomedical Optics 13, 034023 (2008).
Y. Hou, S. Ashkenazi, S.-W. Huang, and M. O’Donnell, “All-optical Theta-array for 3D Ultrasound Imaging”, submitted to IEEE Trans. Ultrason. Ferroelect. Freq. Contr. (2008).
Y. Hou, S.-W. Huang, S. Ashkenazi, R. Witte, and M. O’Donnell, “Thin polymer etalon arrays for high-resolution photoacoustic imaging”, submitted to IEEE Trans. Ultrason. Ferroelect. Freq. Contr. (2008).
X. Yang, E. Stein, S. Ashkenazi, and L. V. Wang “Nanoparticle for Photoacoustic Imaging”, to appear in Wiley Interdisciplinary Reviews: Nanomedicine (Invited review article).
A. Maxwell, S.-W. Huang, T. Ling, J.-S. Kim, S. Ashkenazi, and L. J. Guo, “Polymer Microring Resonators for High-Frequency Ultrasound Detection and Imaging”, IEEE Journal of Selected Topics in Quantum Electronics, 14(1), p.191 (2008).
A. Agarwal, S. W. Huang, M. O’Donnell, K. C. Day, M. Day, N. Kotov, and S. Ashkenazi, “Targeted gold nano-rod contrast agent for prostate cancer detection by photoacoustic imaging”, J. Appl. Phys. 102, 064701 (2007).
S. Ashkenazi, Y. Hou, S.-W. Huang, T. Buma, and M. O’Donnell, “High frequency optoacoustic transducers for ultrasonic and photoacoustic imaging”, in Photoacoustic imaging ed. L. V. Wang (invited book chapter).
G. Kim, S. W. Huang, M. O’Donnell, R. Agayan, K. Day, M. Day, R. Kopelman and S. Ashkenazi, “Indocyanine Green embedded PEBBLEs as a Contrast Agent for Photoacoustic Imaging”, Journal of Biomedical Optics 12 (4) 044020 July/August (2007).
Y. Hou, J.-S. Kim, S. Ashkenazi, S.-W. Huang, L. J. Guo, and M. O'Donnell, “Broadband all-optical ultrasound transducers”, Appl. Phys. Lett. 91, 073507 (2007).
Y. Hou, J.-S. Kim, S.-W. Huang, S. Ashkenazi, L. J. Guo, and M. O’Donnell, “Characterization of a broadband all-optical ultrasound transducer – from optical and acoustical properties to imaging”, accepted for publication in IEEE Trans. Ultrason, Ferroelect. Freq. Contr. (2007).
C. Y. Chao, S. Ashkenazi, S. W. Huang, M. O’Donnell, and L. J. Guo, “High-frequency ultrasound sensors using polymer microring resonators”, IEEE Trans. Ultrason, Ferroelect. Freq. Contr. 54,(5) pp. 957 – 965 (2007).
Y. Hou, S. Ashkenazi, and M. O’Donnell, “Improvements in Optical Generation of High Frequency Ultrasound”, IEEE Trans. Ultrason. Ferroelect. Freq. Contr. 54, (3) pp. 682-686 (2007).
Y. Hou, J. S. Kim, S. Ashkenazi, M. O’Donnell, and L. J. Guo, “Optical generation of high frequency ultrasound using two-dimensional gold nanostructure”, Appl. Phys. Lett. 89, pp. 093901 (2006).
S. Ashkenazi, Y. Hou, T. Buma and M. O'Donnell, “Optoacoustic imaging using thin polymer etalon”, Appl. Phys. Lett. 86, pp. 134102-1-3 (2005).
S. Ashkenazi, C. Y. Chao, L. J. Guo, and M. O’Donnell, “Ultrasound detection using polymer microring optical resonator”, Appl. Phys. Lett. 85, pp. 5418-20 (2004).
S. Lukaschuk, S. Ashkenazi, V. Lebedev and V. Steinberg, “New light scattering technique based on phase time derivative correlation function”, Europhysics Letters 56, pp. 808 (2001).
S. Ashkenazi and V. Steinberg, “Spectra and statistics of velocity and temperature fluctuations in turbulent convection”, Physical Review Letters 83, pp. 4760 (1999).
S. Ashkenazi and V. Steinberg, “High Rayleigh number turbulent convection in a gas near the gas-liquid critical point”, Physical Review Letters 83, pp. 3641 (1999).
S. Ashkenazi and E. Polturak, “An acoustic laboratory experiment to determine the coefficient of mutual diffusion of gases”, American Journal of Physics 56, pp. 836 (1988).