Professor Justin DuBois
Professor Justin DuBois
School of Humanities & Sciences
Stanford University
Using Chemistry to Study Voltage-Gated Ion Channels
We are interested in understanding the role of sodium channels in nociception, work that may ultimately inform the development of new analgesic medicines. Our studies rely on molecular biology and electrophysiology to measure ionic currents in cells and capitalize on the availability of potent neurotoxins and derivatives thereof as selective reagents for manipulating channel function. This lecture will focus specifically on efforts to 'map' toxin-channel receptor sites and to design tool compounds that target and enable regulation of select channel subtypes.
Professor Justin DuBois
Justin Du Bois was born August 23, 1969 in Los Angeles, California. He received his B.S. degree from the University of California, Berkeley in 1992, where he conducted undergraduate research with Professor Ken Raymond. In 1997 he earned his Ph. D. from the California Institute of Technology under the direction of Professor Erick Carreira. Following a two year NIH postdoctoral position with Professor Stephen Lippard at MIT, he joined the faculty at Stanford University as an assistant professor. In 2005, he was promoted to the associate level. In addition, Justin is faculty by courtesy in the Dept. of Chemical & Systems Biology at Stanford University, a founding member of the NSF Center for Selective C-H Functionalization, an executive committee member of the Stanford Institute for Chemical Biology, and the founder of the Center for Molecular Analysis and Design at Stanford University.