Professor Renã AS Robinson

Professor Renã AS Robinson
Dorothy J. Wingfield Phillips Chair
Department of Chemistry
Vanderbilt University
Printable Abstract

Pushing the Limits of Quantitative Proteomics to Advance Alzheimer’s Disease Research

Large-scale proteomics studies of clinical samples and animal models are readily increasing across disease applications, including in Alzheimer’s disease (AD). These studies require diversity in cohorts, accessible sample types, multiple disease timepoints, robust analytical workflows, and high-throughput capabilities in order to have the greatest impact towards disease understanding and discovery efforts. Our laboratory has been working in the last few years to address these requirements primarily to advance health disparities research in Alzheimer’s disease. Bottom-up proteomic workflows leveraging in-house and commercial isotopic and isobaric labeling strategies, sample preparation automation, and high-resolution mass spectrometry have been developed. Importantly, to handle sample sizes (>1000), standard operating procedures and quality control measures have been implemented in our proteomics workflows.

Renã AS Robinson

Dr. Renã A. S. Robinson, Professor of Chemistry at Vanderbilt University and inaugural Dorothy J. Wingfield Phillips Chair, received her B.S. in Chemistry with concentration in Business and Ph.D. in Analytical Chemistry. She has a nationally and internationally recognized research program and is a leader in the field of proteomics for her work in aging, Alzheimer’s disease, and applications relevant to human health. Her laboratory is especially focused on advancing proteomics and lipidomics technologies to promote health equity in Alzheimer’s disease. Renã serves as the Immediate Past President of NOBCChE (National Organization for the Professional Advancement of Black Chemists and Chemical Engineers) where she led the organization through tremendous growth in membership, programming, funding, and overall outreach of URMs in STEM. She is the former faculty advisor for the Nashville Student and Professional Chapter of NOBCChE, and currently Co- Director for the Faculty ACCESS Program, and Board Member-at-Large for the US Human Proteome Organization.

Hosted by Professor Varun Gadkari