Lawrence "Larry" Que Jr.

Lawrence "Larry" Que Jr.
Regents Professor, Distinguished University Teaching Professor, Department of ChemistryContact
Smith Hall Room 343 207 Pleasant Street SeMinneapolis, MN 55455
Affiliations
Education
B.S. Ateneo de Manila University, 1969
Ph.D. University of Minnesota, 1973 (Louis H. Pignolet)
Post Doctorate Massachusetts Institutes of Technology (Richard H. Holm), University of Minnesota (Eckard Münck), 1973-1977
Inorganic & Organometallic Chemistry: bioinorganic chemistry
Chemical Biology: nonheme iron enzymes
Environmental & Green Chemistry: enzymatic oxidation
Energy & Catalysis
Our group focuses on bio-inorganic chemistry, specifically on the topic of iron, oxygen and (bio)catalysis. Our research effort, involving a combination of biochemical, synthetic inorganic, and spectroscopic approaches, is aimed at elucidating the oxygen activation mechanisms of nonheme iron enzymes, designing functional models for such enzymes, trapping and characterizing reaction intermediates, and developing bio-inspired oxidation catalysts for green chemistry applications. The pictures illustrate the crystal structure of a recently isolated oxoiron(IV) complex with the oxo atom syn to the methyl groups of the TMC macrocycle and a DFT-calculated structure for a reactive intermediate that we have trapped in our efforts to develop bio-inspired iron catalysts for hydrocarbon oxidation.


Honors and Awards
American Chemical Society Award in Inorganic Chemistry, 2017
Japan Society of Coordination Chemistry International Award, 2015
John C. Bailar Jr. Medal from University of Illinois Urbana-Champaign, 2012
Elected American Chemical Society Fellow, 2011
Royal Society of Chemistry Inorganic Reaction Mechanisms Award, 2011
Designated Fellow of the Royal Society of Chemistry, 2008
American Chemical Society Alfred Bader Award in Bioinorganic or Bioorganic Chemistry, 2008
Frontiers in Biological Chemistry Award from the Max-Planck-Institut für Bioanorganishe Chemie, 2005
Elected Fellow of the American Association for the Advancement of Science, 2001
National Institutes of Health MERIT Award, 2000-2010
University of Minnesota Award for Outstanding Contributions in Post-Baccalaureate, Graduate, and Professional Education, 1999-2000
National Institutes of Health Research Career Development Award, 1982-1987
Alfred P. Sloan Research Fellowship, 1982-1986
Mailing Address
Lawrence Que
University of Minnesota
Department of Chemistry
B-16, 139 Smith Hall, 207 Pleasant St SE
Minneapolis, MN 55455-0431