Du’s current research focuses on intelligent storage systems, sensor/vehicular networks and cyber physical systems. He has had research in high-speed networking, database design, multimedia computing and CAD for VLSI circuits. He has authored and co-authored over 300 technical papers including 140 referred journal publications in these research areas. He has graduated 60 Ph.D. and 100+ M.S. students in the last 30 years. His research in intelligent storage systems focus on new storage technologies/architectures, that can handle semantic data and adaptive to long-term data preservation, and efficient power management for data centers. His research in sensor/vehicular networks and cyber physical systems focuses on vehicle-to-vehicle communications, future intelligent transportation systems, next generation air-transportation systems and security and privacy issues for cyber physical systems. His group is currently focusing on research issues on hyperconverging (seamless integrating compute, storage and network in a single IT infrastructure and using AI and machine learning approaches of solving challenging systems management issues.