Latest research projects, publications, and talks
Machine learning and statistical methods for clustering single-cell RNA-sequencing data [journal]
Posted
Raphael Petegrosso (Ph.D. 2019), Zhuliu Li (Ph.D. student), Rui Kuang (associate professor)
Briefings in Bioinformatics
Exploring whole-genome duplicate gene retention with complex genetic interaction analysis [journal]
Posted
Elena Kuzmin, Benjamin VanderSluis (researcher), Alex N Nguyen Ba, Wen Wang (researcher), Elizabeth N Koch (Ph.D. student), Matej Usaj, Anton Khmelinskii, Mojca Mattiazzi Usaj, Jolanda van Leeuwen, Oren Kraus, Amy Tresenrider, Michael Pryszlak, Ming-Che Hu, Brenda Varriano, Michael Costanzo, Michael Knop, Alan Moses, Chad L Myers (professor), Brenda J Andrews, Charles Boone
Science Magazine
A guide to diet-microbiome study design [journal]
Posted
Abigail J Johnson, Jack Jingyuan Zheng, Jea Woo Kang, Anna Saboe, Dan Knights (professor), Angela M Zivkovic
Frontiers in Nutrition
Dbf4-Dependent Kinase (DDK)-Mediated Proteolysis of CENP-A Prevents Mislocalization of CENP-A in Saccharomyces cerevisiae [journal]
Posted
Jessica R Eisenstatt, Lars Boeckmann, Wei-Chun Au, Valerie Garcia, Levi Bursch, Josefina Ocampo, Michael Costanzo, Michael Weinreich, Robert A Sclafani, Anastasia Baryshnikova, Chad L Myers (professor), Charles Boone, David J Clark, Richard Baker, Munira A Basrai
G3: Genes, Genomes, Genetics
Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism [journal]
Posted
Michael Aregger, Keith A Lawson, Maximillian Billmann, Michael Costanzo, Amy HY Tong, Katherine Chan, Mahfuzur Rahman, Kevin R Brown, Catherine Ross, Matej Usaj, Lucy Nedyalkova, Olga Sizova, Andrea Habsid, Judy Pawling, Zhen-Yuan Lin, Hala Abdouni, Cassandra J Wong, Alexander Weiss, Patricia Mero, James W Dennis, Anne-Claude Gingras, Chad L Myers (professor), Brenda J Andrews, Charles Boone, Jason Moffat
Nature Metabolism
EXO1 resection at G-quadruplex structures facilitates resolution and replication [journal]
Posted
Susanna Stroik, Kevin Kurtz, Kevin Lin, Sergey Karachenets, Chad L Myers (professor), Anja-Katrin Bielinsky, Eric A Hendrickson
Nucleic Acids Research
Identification of nodulation‐related genes in Medicago truncatula using genome‐wide association studies and co‐expression networks [journal]
Posted
Jean‐Michel Michno, Junqi Liu, Joseph R Jeffers, Robert M Stupar, Chad L Myers (professor)
Plant Direct
Sex bias in gut microbiome transmission in newly paired marmosets (Callithrix jacchus) [journal]
Posted
Lifeng Zhu, Jonathan B Clayton, Mallory J Suhr Van Haute, Qinnan Yang, Haley R Hassenstab, Aaryn C Mustoe, Dan Knights (professor), Andrew K Benson, Jeffrey A French
Msystems
Platform-integrated mRNA isoform quantification [journal]
Posted
Jiao Sun, Jae-Woong Chang, Teng Zhang, Jeongsik Yong, Rui Kuang (associate professor), Wei Zhang
Bioinformatics
Uncovering and Exploiting HUH‐endonuclease ssDNA Recognition for Protein‐DNA Bioconjugation [journal]
Posted
Kassidy Tompkins, Andrew Nelson, Lauren Litzau, Blake Everett, Mohamed Houtti (Ph.D. student), Leland Pornschloegl, Andrew Lemmex, Lidia Swanson, Eric Aird, Robert Evans III, Dan Knights (professor), Wendy Gordon
The FASEB Journal